Battle of Bicocca

Date: April 27, 1522 • Location: Sesto San Giovanni, Italy

Four Years' War: The combined forces of Spain and the Papal States defeated a French and Venetian army at the Battle of Bicocca.

The Italian War of 1521–1526, sometimes known as the Four Years' War, was a part of the Italian Wars. The war pitted Francis I of France and the Republic of Venice against the Holy Roman Emperor Charles V, Henry VIII of England, and the Papal States. It arose from animosity over the election of Charles as Emperor in 1519–1520 and from Pope Leo X's need to ally with Charles against Martin Luther.